Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Barry Dean Wellborn, Deborah Lea Smith, Dezi Ann Koster, Elizabeth Patric, Jagdish Singh, Kathleen Starr Vagt, Krista Joanne Callas, Parthasarathi Panda, Kalyan Kumar Sethi, Snehasis Jana

Zinc chloride is an important pharmaceutical/nutraceutical compound used as a source of zinc. The objective of the current study was to investigate the impact of The Trivedi Effect®-Energy of Consciousness Healing Treatment (Biofield Energy Treatment) on physical, structural, thermal, and behavioral properties of zinc chloride using PXRD, PSD, FT-IR, UV-vis, and DSC analysis. Zinc chloride was divided into two parts – one part was control, while another part was treated with The Trivedi Effect® remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. A significant alteration of the crystallite size and relative intensities of the PXRD peaks was observed in The Trivedi Effect® treated sample compared with the control sample. A sharp peak at 2θ equal to 16.58° was observed in the control sample, but it was disappeared in the treated sample. The average crystallite size of the treated sample was significantly reduced by 21.31% compared with the control sample. The particle size values at d10, d50, and d90 were significantly decreased by 8.15%, 6.28%, and 5.26%, respectively in the treated sample compared with the control sample. The surface area of the treated sample was significantly increased by 7.14% compared with the control sample. The FT-IR spectroscopic analysis revealed that Zn-Cl stretching in the control and treated sample were found at 510 cm-1 and 511 cm-1, respectively. The UV-vis analysis exhibited that wavelength of the maximum absorbance (λmax) of both the control and treated samples was at 196 nm. The DSC analysis exhibited that the melting and decomposition temperature were decreased by 0.29% and 0.28%, respectively in the treated zinc chloride compared to the control sample. The latent heat of fusion of the treated sample (370.48 J/g) was increased significantly by 97.71% compared with the control sample (187.39 J/g). This results indicated that zinc chloride need more heat energy to undergo the process of melting after Biofield Energy Treatment. The enthalpy of decomposition of the treated sample was significantly decreased by 15.40% compared with the control sample. The current study anticipated that The Trivedi Effect®-Energy of Consciousness Healing Treatment might lead to produce a new polymorphic form of zinc chloride, which would be more soluble, bioavailable and latent heat of fusion compared with the untreated compound. Hence, the treated zinc chloride would be very useful to design better nutraceutical/pharmaceutical formulations that might offer better therapeutic response against inflammatory diseases, immunological disorders, aging, stress, cancer, etc.

Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Barry Dean Wellborn, Deborah Lea Smith, Dezi Ann Koster, Elizabeth Patric, Jagdish Singh, Kathleen Starr Vagt, Krista Joanne Callas, Parthasarathi Panda, Kalyan Kumar Sethi, Snehasis Jana

Magnesium gluconate is a potent antioxidant and widely used for the prevention and treatment of hypomagnesia. The current research was aimed to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment on magnesium gluconate for the change in the physicochemical, structural, thermal and behavioral properties using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Magnesium gluconate was divided into two parts – one part was control without any Biofield Energy Treatment, while another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. The PXRD analysis exhibited that the crystallite size of the treated sample was remarkably changed from - 24.96% to 99.98% compared with the control sample. The average crystallite size was significantly increased by 7.79% in the treated sample compared with the control sample. PSD analysis revealed that the particle sizes in The Trivedi Effect® Treated sample at d10, d50 and d90 values were decreased by 5.36%, 11.35% and 0.90%, respectively compared with the control sample. The surface area analysis revealed that surface area of the Biofield Energy Treated sample was significantly increased by 7.48% compared with the control sample. The FT-IR and UV-vis analysis showed that structure of the magnesium gluconate remained the same in both the treated and control samples. The TGA analysis revealed four steps thermal degradation of both the samples and the total weight loss of Biofield Energy Treated sample was increased by 0.12% compared with the control sample. The DSC analysis demonstrated that the melting temperature of the Biofield Energy Treated sample (171.29°C) was increased by 0.18% compared with the control sample (170.99°C). The latent heat of fusion was significantly increased by 27.09% in the treated sample compared with the control sample. The current study revealed that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) might lead to a new polymorphic form of magnesium gluconate, which would be more soluble, bioavailable, and thermally stable compared with the untreated compound. The Biofield Treated sample could be more stable during manufacturing, delivery or storage conditions than the untreated sample. Hence, The Trivedi Effect® Treated magnesium gluconate would be very useful to design better nutraceutical and/or pharmaceutical formulations that might offer better therapeutic responses against inflammatory diseases, immunological disorders, stress, aging, and other chronic infections.

Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, William Dean Plikerd, Peter L. Surguy, Robert John Kock, Rolando Baptista Piedad, Russell Phillip Callas, Sakina A. Ansari, Sandra Lee Barrett, Sara Friedman, Steven Lee Christie, Su-Mei Chen Liu, Susan Elizabeth Starling, Susan Jones, Susan Mardis Allen, Susanne Kathrin Wasmus, Terry Ann Benczik, Thomas Charles Slade, Thomas Orban, Victoria L. Vannes, Victoria Margot Schlosser, Yusif Sarkis Yamin Albino, Parthasarathi Panda, Kalyan Kumar Sethi, Snehasis Jana

Magnesium gluconate is widely used pharmaceutical/nutraceutical compound for the prevention and treatment of magnesium deficiency diseases. The present study was designed to explore the effect of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the structural properties and isotopic abundance ratio (PM+1/PM and PM+2/PM) using LC-MS and NMR spectroscopy. Magnesium gluconate was divided into two parts – one part was control, and another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by twenty renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample. The LC-MS analysis of both the control and Biofield Energy Treated samples indicated the presence of mass of the protonated magnesium gluconate at m/z 415 at the retention time of 1.52 min and fragmentation pattern of both samples were almost identical. The relative peak intensities of the fragment ions were significantly altered in the treated sample compared to the control sample. The proton and carbon signals for CH, CH2 and CO groups in the proton and carbon NMR spectra of the control and treated samples were found same. The percentage change in the isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 17O/16O or 25Mg/24Mg) was significantly decreased in the treated sample by 48.87% compared to the control sample. Subsequently, the isotopic abundance ratio of PM+2/PM (18O/16O or 26Mg/24Mg) in the treated sample was significantly increased by 29.18% compared with the control sample. In summary, 13C, 2H, 17O, and 25Mg contributions from (C12H23MgO14)+ to m/z 416; 18O and 26Mg contributions from (C12H23MgO14)+ to m/z 417 in the treated sample were significantly altered compared with the control sample. Thus, The Trivedi Effect® Treated magnesium gluconate might be helpful to design the novel potent enzyme inhibitors using its kinetic isotope effects. Consequently, The Trivedi Effect® Treated magnesium gluconate would be valuable for designing better pharmaceutical and/or nutraceutical formulations through its altered physicochemical and thermal properties, which might be providing better therapeutic response against various diseases such as diabetes mellitus, allergy, aging, inflammatory diseases, immunological disorders, and other chronic infections.

Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, William Dean Plikerd, Peter L. Surguy, Robert John Kock, Rolando Baptista Piedad, Russell Phillip Callas, Sakina A. Ansari, Sandra Lee Barrett, Sara Friedman, Steven Lee Christie, Su-Mei Chen Liu, Susan Elizabeth Starling, Susan Jones, Susan Mardis Allen, Susanne Kathrin Wasmus, Terry Ann Benczik, Thomas Charles Slade, Thomas Orban, Victoria L. Vannes, Victoria Margot Schlosser, Yusif Sarkis Yamin Albino, Kalyan Kumar Sethi, Parthasarathi Panda, Snehasis Jana

Sodium selenate is an inorganic nutraceutical/pharmaceutical compound used for the prevention and treatment of several diseases. The current research article was aimed to explore the effect of The Trivedi Effect® - Energy of Consciousness Healing Treatment on the physicochemical, spectral, thermal, and behavioral properties of sodium selenate using PXRD, PSD, FT-IR, UV-vis, TGA, and DSC analysis. Sodium selenate was divided into two parts – one part was control, while another part was The Trivedi Effect® Treated sample which was received The Trivedi Effect® remotely by twenty renowned Biofield Energy Healers. A significant alteration of the crystallite size of the treated sample was observed in the range of -42.87% to 39.99% compared to the control sample. Consequently, the average crystallite size was significantly enhanced in the treated sample by 5.07% compared with the control sample. The particle size distribution of the treated sample at d10, d50, and d90 values were significantly reduced by 7.68%, 9.49%, and 4.08%, respectively compared with the control sample. Subsequently, the surface area of the treated sample was significantly increased by 8.16% compared with the control sample. The control and treated FT-IR spectra exhibited the sharp and strong vibration bands at 889 cm-1 and 888 cm-1, respectively for Se=O stretching. The control and treated samples displayed the maximum absorbance at 204.9 nm and 204.5 nm, respectively. A significant reduction of total weight loss by 6.11% in the treated sample indicated the improvement of the thermal stability of the treated sample compared with the control sample. The vaporization temperature of the treated sample (95.68°C) was higher with a significant reduced latent heat of vaporization by 60.80% compared to the control sample (95.29°C). Thus, The Trivedi Effect® - Energy of Consciousness Healing Treatment might produce a new polymorphic form of sodium selenate which would be more soluble, dissolution rate, bioavailable, and thermally stable compared with the untreated sample. The Trivedi Effect® treated sodium selenate would be very suitable to design improved nutraceutical and pharmaceutical formulations that might provide better therapeutic response against several diseases such as stress, aging, inflammatory diseases, immunological disorders, infectious diseases, cancer, etc.