Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Parthasarathi Panda, Snehasis Jana

1,2,3-Trimethoxybenzene (TMB) is one of the most versatile chemical used for the synthesis of several pharmaceuticals, dyes, polymers, organic compounds, etc. The stable isotope ratio analysis has increased attention day-by-days in several fields such as agricultural, food authenticity, biochemistry, medical research, etc. The current study was aimed to evaluate the effect of the biofield energy treatment on the isotopic abundance ratios of 13C/12C or 2H/1H or 17O/16O (PM+1/PM) and 18O/16O (PM+2/PM) in TMB using Gas chromatography - mass spectrometry (GC-MS) technique. TMB was divided into two parts - one part was denoted as control and another part was referred as biofield energy treated sample that was received through Mr. Trivediꞌs unique biofield energy (The Trivedi Effect®). The GC-MS of the biofield treated TMB was characterized at different time intervals considered as T1, T2, T3, and T4 to examine the impact of the biofield energy treatment on isotopic abundance ratio with respect to the time. The GC-MS spectra of the both control and biofield treated TMB exhibited the presence of molecular ion peak [M+] at m/z 168 (calculated 168.08 for C9H12O3) along with similar pattern of fragmentation. The relative peak intensities of the fragmented ions in the biofield treated TMB, particularly at T2 and T3 was altered from the control sample. The isotopic abundance ratio analysis in the biofield treated TMB exhibited that the isotopic abundance ratio of PM+1/PM in the biofield treated TMB at T2 and T3 was significantly enhanced by 128.13 and 117.99%, respectively with respect to the control sample. Consequently, the percentage change in isotopic abundance ratio of PM+2/PM was significantly increased in the biofield treated TMB at T2 and T3 by 125.93 and 116.67%, respectively as compared with the control TMB. The isotopic abundance ratios (PM+1/PM and PM+2/PM) in the biofield treated TMB at T1 and T4 was altered with respect to the control TMB. In summary, 13C, 2H, and 17O contributions from (C9H12O3)+ to m/z 169 and 18O contribution from (C9H12O3)+ to m/z 170 for the biofield treated TMB, particularly at T2 and T3 were significantly improved and biofield treated TMB might exhibit changed isotope effects as compared to the control sample. The biofield treated TMB might assist to develop new chemicals and pharmaceuticals through using its kinetic isotope effects like understanding the reaction mechanism, the enzymatic transition state and all aspects of enzyme mechanisms.

Mahendra Kumar Trivedi, Alice Branton, Dahryn TrivediMahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Kalyan Kumar Sethi, Snehasis Jana

The objective of the current study was to evaluate the effect of biofield energy treatment on the isotopic abundance ratios of PM+1/PM, PM+2/PM, PM+3/PM and PM+4/PM in p-DCB using gas chromatography-mass spectrometry (GC-MS). The p-DCB was divided into two parts - one part was control sample, and another part was considered as the treated sample which was subjected to biofield energy treatment (The Trivedi Effect®). T1, T2, T3, and T4 were referred the biofield treated p-DCB having analyzed at different time intervals. The GC-MS analysis of both the control and biofield treated p-DCB indicated the presence of the parent molecular ion peak at m/z 146 along with four major fragmentation peaks at m/z 111, 75, 55 and 50. The relative peak intensities of the fragmented ions in the biofield treated p-DCB were notably changed as compared to the control sample with respect to the time. The isotopic abundance ratio analysis using GC-MS revealed that the isotopic abundance ratio of PM+1/PM at T1, T2, T3, and T4 (biofield energy treated p-DCB) was significantly increased by 10.87, 83.90, 225.16, and 241.15%, respectively as compared to the control sample. Consequently, the percentage change in the isotopic abundance ratio of PM+2/PM at T1, T2, and T3 (biofield energy treated p-DCB) was enhanced by 4.55, 9.49, and 1.80%, respectively as compared to the control sample. Beside these, another two isotopic molecular ion peaks at m/z 149 and 150 were found in the GS-MS spectra due to arise from the contributions of various combinations of 2H, 13C, and 37Cl. The isotopic abundance ratios of PM+3/PM in biofield energy treated sample at T1, T2, T3, and T4 was significantly increased by 15.14, 82.57, 192.43, and 218.31%, respectively as compared to the control sample. Similarly, the PM+4/PM in biofield energy treated sample at T1, T2, T3, and T4 was significantly increased by 13.80, 86.66, 186.13, and 204.29%, respectively as compared to the control sample. Overall, the isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C), PM+2/PM (37Cl/35Cl), for PM+3/PM and PM+4/PM (the probable combinations of 2H/1H, 13C/12C, and 37Cl/35Cl) were significantly enhanced in the biofield energy treated p-DCB. The biofield treated p-DCB has shown improved isotopic abundance ratios that might have altered the physicochemical properties, thermal properties and rate of reaction. Biofield treated p-DCB might be useful in pharmaceutical and chemical industries as intermediates during the manufacturing of pharmaceuticals and chemicals by monitoring the rate of chemical reaction.

Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Parthasarathi Panda, Snehasis Jana

p-tert-Butyphenol (PTBP) is a phenolic monomer used in the synthesis of numerous industrially useful chemicals. The current research work aimed to evaluate the effect of the biofield energy treatment on the isotopic abundance ratios of PM+1/PM and PM+2/PM in PTBP using gas chromatography - mass spectrometry (GC-MS). The sample, PTBP was distributed into two parts - one part was designated as control PTBP and another part was considered as biofield energy treated PTBP. The biofield energy treatment was achieved through unique biofield energy transmission process by Mr. Trivedi (also known as The Trivedi Effect®). T1, T2, T3, and T4 were indicated to the different time interval analysis of the biofield treated PTBP. The GC-MS spectra of the both control and biofield treated PTBP showed the presence of molecular ion peak [M+] at m/z 150 (calculated 150.10 for C10H14O) along with eight major fragmented peaks at m/z 135, 107, 95, 91, 77, 65, 41, and 39, which might be due to C10H15+, C7H7O+ or C8H11+, C6H7O+, C7H7+, C6H5+, C5H5+, C3H5+, and C3H3••+ ions, respectively. The relative intensities of the parent molecule and other fragmented ions of the biofield treated PTBP were altered as compared to the control PTBP. The percentage in the isotopic abundance ratio of PM+1/PM was enhanced in the biofield treated PTBP at T2, T3 and T4 by 1.60%, 3.57%, and 120.13%, respectively while it was decreased by 4.14% in the treated sample at T1 with respect to the control PTBP. Consequently, the isotopic abundance ratio of PM+2/PM was increased in the biofield treated PTBP at T1, T3, and T4 by 1.28%, 2.56%, and 123.08%, respectively with respect to the control sample. On the other hand, it was reduced in the biofield treated sample at T2 by 1.28% as compared to the control PTBP. Concisely, 13C, 2H, and 17O contributions from (C10H14O)+ to m/z 151 and 18O contribution from (C10H14O)+ to m/z 152 in the biofield treated PTBP were changed with respect to the control sample and was found to have time dependent effect. The biofield energy treated PTBP might display isotope effects such as different physicochemical and thermal properties, rate of the reaction, selectivity and binding energy due to the changed isotopic abundance ratio as compared to the control sample. Biofield treated PTBP could be valuable for the designing new chemicals and pharmaceuticals through using its kinetic isotope effects.

Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Kalyan Kumar Sethi, Snehasis Jana

Methyl-2-napthylether (nerolin) is an organic compound and has the applications in pharmaceutical, and perfume industry. The stable isotope ratio analysis is increasing importance in various field of scientific research. The objective of the current study was to evaluate the effect of the biofield energy treatment on the isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 17O/16O) and PM+2/PM (18O/16O) in nerolin using the gas chromatography-mass spectrometry (GC-MS). The compound nerolin was divided into two parts - one part was control sample (untreated), and another part was considered as biofield energy treated sample which was received the biofield energy treatment through the unique biofield energy transmission process by Mr. Mahendra Kumar Trivedi (also known as The Trivedi Effect®). The biofield energy treated nerolin was analyzed at different time intervals and were represented as T1, T2, T3, and T4 in order to understand the effect of the biofield energy treatment on isotopic abundance ratio with respect to the time. From the GC-MS spectral analysis, the presence of the molecular ion peak C11H10O+ (m/z 158) along with major fragmented peaks C10H7O- (m/z 143), C10H8 (m/z 128), C9H7+ (m/z 115), C7H5+ (m/z 89), C5H3+ (m/z 63), C4H3+ (m/z 51), and C3H3+ (m/z 39) were observed in both control and biofield treated samples. Only, the relative peak intensities of the fragmented ions in the biofield treated nerolin was notably changed as compared to the control sample with respect to the time. The isotopic abundance ratio analysis of nerolin using GC-MS revealed that the isotopic abundance ratio of PM+1/PM in the biofield energy treated nerolin at T1, T2, T3, and T4 was increased by 2.38, 138.10, 13.10, and 32.14%, as compared to the control sample. Likewise, the isotopic abundance ratio of PM+2/PM at T1, T2, T3, and T4 was increased by 2.38, 138.10, 13.10, and 32.14%, respectively in the biofield treated nerolin as compared to the control sample. Overall, the isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 17O/16O) and PM+2/PM (18O/16O) were significantly increased in the biofield energy treated sample as compared to the control sample with respect to the time. It is concluded that Mr. Trivedi’s biofield energy treatment has the significant impact on alteration in isotopic abundance of nerolin as compared to the control sample. The biofield treated nerolin might display different altered physicochemical properties and rate of reaction and could be an important intermediate for the production of pharmaceuticals, chemicals, and perfumes in the industry.